Microscopes

We talk about macroscopy when describing imaging methods that look at objects visible to the naked eye, i.e. a few cm to mm.

A widefield microscope is a camera-based system that takes an image of the whole field of view at once.  

Multiplex systems image the same sample beyond the traditional 3-5 labels. This has the advantage of profiling precious tissue with many markers, which can then be analysed at the single cell level, but also in relation to surrounding cells and tissue.

Slide scanners are widefield microscopes designed for routine imaging of large number of slides.

A confocal microscope uses a pinhole to only allow light from a thin slice of objects in focus to reach a photosensor.  Out of focus light above and below that slice is filtered out.  

Multiphoton confocals work by using an infrared laser at double or triple the wavelength necessary to excite a fluorophore.

Superresolution microscopes are designed to provide details that go beyond the limit of resolution, around 200nm, imposed by diffraction of classic microscopes - confocal or widefield.

Label-free microscopy relies on gentle illumination of samples away from harsh fluorescent light. This allows for imaging, long or short-term, without inducing phototoxicity.

Our selection of TC microscopes.