Selected Publications

2021

Pelvic pain correlates with peritoneal macrophage abundance not endometriosis.

Gibson, D. A., Collins, F., De Leo, B., Horne, A. W., & Saunders, P. T. K.

Reproduction and Fertility. 2(1), 47-57. doi: 10.1530/raf-20-0072

 

High Purity Isolation of Low Density Neutrophils Casts Doubt on Their Exceptionality in Health and Disease.

Hardisty GR, Llanwarne F, Minns D, Gillan JL, Davidson DJ, Gwyer Findlay E and Gray RD.

Front. Immunol. 12:625922. doi: 10.3389/fimmu.2021.625922

 

Photoactivatable metabolic warheads enable precise and safe ablation of target cells in vivo.

Benson, S., de Moliner, F., Fernandez, A. et al.

Nat Commun 12, 2369 (2021). doi: 10.1038/s41467-021-22578-2

 

2020

Kidney Single-Cell Atlas Reveals Myeloid Heterogeneity in Progression and Regression of Kidney Disease.

Bryan R. Conway, Eoin D. O’Sullivan, Carolynn Cairns, James O’Sullivan, Daniel J. Simpson, Angela Salzano, Katie Connor, Peng Ding, Duncan Humphries, Kevin Stewart, Oliver Teenan, Riinu Pius, Neil C. Henderson, Cécile Bénézech, Prakash Ramachandran, David Ferenbach, Jeremy Hughes, Tamir Chandra, Laura Denby.

 

Macrophages inhibit and enhance endometriosis depending on their origin.

Chloe Hogg, Kavita Panir, Priya Dhami, Matthew Rosser, Matthias Mack, Daniel Soong, Jeffrey W. Pollard, Stephen J. Jenkins, Andrew W. Horne, Erin Greaves.

PNAS Feb 2021, 118 (6) e2013776118; DOI: 10.1073/pnas.2013776118

 

Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages.

Bain CC, Gibson DA, Steers NJ, Boufea K, Louwe PA, Doherty C, González-Huici V, Gentek R, Magalhaes-Pinto M, Shaw T, Bajénoff M, Bénézech C, Walmsley SR, Dockrell DH, Saunders PTK, Batada NN, Jenkins SJ.

Sci Immunol. 2020 Jun 19;5(48):eabc4466. doi: 10.1126/sciimmunol.abc4466

 

2019

Gene expression profiling reveals a conserved microglia signature in larval zebrafish.

Mazzolini J, Le Clerc S, Morisse G, et al.

Glia. 2020;68:298–315. doi: 10.1002/glia.23717

 

A role for macrophages in hematopoiesis in the embryonic head.

Zhuan Li, Samanta A. Mariani, et al.

Blood (2019) 134 (22): 1929–1940. doi: 10.1182/blood.2018881243

 

Resolving the fibrotic niche of human liver cirrhosis at single-cell level.

Ramachandran, P., Dobie, R., Wilson-Kanamori, J.R. et al.

Nature 575, 512–518 (2019). doi: 10.1038/s41586-019-1631-3

 

2018

An efficient method to isolate Kupffer cells eliminating endothelial cell contamination and selective bias.

Lynch RW, Hawley CA, Pellicoro A, Bain CC, Iredale JP, Jenkins SJ.

J Leukoc Biol. 2018 Apr 1. doi: 10.1002/JLB.1TA0517-169R. 

 

2017

Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses.

Sadiku P, Willson JA, Dickinson RS, Murphy F, Harris AJ, Lewis A, Sammut D, Mirchandani AS, Ryan E, Watts ER, Thompson AAR, Marriott HM, Dockrell DH, Taylor CT, Schneider M, Maxwell PH, Chilvers ER, Mazzone M, Moral V, Pugh CW, Ratcliffe PJ, Schofield CJ, Ghesquiere B, Carmeliet P, Whyte MK, Walmsley SR.

J Clin Invest. 2017 Sep 1;127(9):3407-3420. doi: 10.1172/JCI90848. Epub 2017 Aug 14.

 

2016

High-fat diet disrupts metabolism in two generations of rats in a parent-of-origin specificmanner.

Chambers TJG, Morgan MD, Heger AH, Sharpe RM, Drake AJ.

Sci Rep. 2016 Aug 23;6:31857. doi: 10.1038/srep31857

 

2015

Circulating IgM Requires Plasma Membrane Disruption to Bind Apoptotic and Non-Apoptotic Nucleated Cells and Erythrocytes.

Hesketh EE, Dransfield I, Kluth DC, Hughes J.

PLoS ONE. 10(6): e0131849. doi:10.1371/journal.pone.0131849

 

2014

Recombinant Ad35 adenoviral proteins as potent modulators of human T cell activation.

Hay J, Carter D, Lieber A, Astier AL.

Immunology. 2014 Sep 22. doi: 10.1111/imm.12391