CIR seminars: Dr Borko Amulic

Fine tuning the neutrophil response for improved infection outcome”

Dr Borko Amulic, Associate Professor in Immunology, School of Cellular and Molecular Medicine, University of Bristol

Dr Amulic webpage  

Host: Dr Sonja Vermeren

** please remember attendance at these seminars is compulsory for all students registered in the CIR as part of your continued development and educational training**

Bio:

PhD Cornell University, New York
EMBO Fellow, Max Planck Institute for Infection Biology
Medical Research Council Career Development Fellow
Co-lead, Infection and Immunity Steering Committee

Research interests:

Regulation of neutrophil development and function

Neutrophils are essential immune cells with important roles in defence against pathogens. They rapidly migrate to sites of infection and kill microbes by phagocytosis, ROS production, degranulation and release of neutrophil extracellular traps (NETs). Absence of neutrophils results in severe immunodeficiency. On the other hand, excessive or dysregulated neutrophil responses are destructive and promote inflammatory pathology in malaria, autoimmunity and cancer. Mechanisms that fine-tune neutrophil responses are therefore critical for health.

We aim to understand how neutrophils are regulated and to use these insights to interrogate their function in infection and inflammation. We also aim to develop therapies targeting neutrophils in malaria, a devastating disease that affects millions of people in the global South.

PLEASE NOTE THERE IS NO STUDENT MEET THE SPEAKER SESSION FOLLOWING THIS SEMINAR

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CIR